Fourth Ecumenical Council held in 451 AD at Chalcedon (modern Kadikoy, Turkey); defined Christ's two natures — divine and human — as existing 'without confusion, without change, without division, without separation' in one person; rejected Monophysitism.
Established Chalcedonian Christology and the doctrine of the hypostatic union as orthodox Christian teaching; defined the theological boundary between mainstream Christianity (Catholic, Eastern Orthodox, Protestant) and the Oriental Orthodox churches (Coptic, Ethiopian, Armenian, Syriac).
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