Hungarian-American physicist who won the Nobel Prize in 1963 and posed two famous philosophical puzzles: Wigner's Friend (a challenge to the Copenhagen interpretation of quantum mechanics) and the unreasonable effectiveness of mathematics.
Wigner's Friend: if quantum measurement collapses the wave function, who collapses it when the observer is observed? — a challenge to consciousness-based collapse interpretations. The Unreasonable Effectiveness of Mathematics: why does pure mathematics, developed without regard to the physical world, describe physical reality so precisely?
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