Hungarian physician who discovered in 1847 that doctors washing hands between autopsies and deliveries dramatically reduced childbed fever mortality — and whose discovery was rejected by the medical establishment, leading to his mental breakdown and death, vindicating the importance of institutional courage in science.
Provided the first rigorous epidemiological evidence for germ transmission before germ theory was formulated — showing that mortality rates fell from ~10% to ~1% with handwashing — but was rejected because his evidence contradicted prevailing theory and implicated respected physicians.
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