The Psychology of Fear and Stress

Jeffrey Gray's systematic account of the psychology and neuroscience of anxiety — integrating behavioral, pharmacological, and neurological evidence into a theory of the anxiety system.

Behavioral Inhibition System (BIS): a neural system that responds to signals of punishment, non-reward, and novelty by inhibiting behavior — the neural substrate of anxiety. Integrates animal learning experiments, pharmacology (anxiolytics), and neuroanatomy (septo-hippocampal system). A precursor to Gray and McNaughton's later two-system (BIS/BAS) theory.